Author Topic: Prediction of Non B-DNA structure (Read 88394 times)

mahesh · « **on:** August 17, 2013, 12:09:29 am »

Hi, is it possible to predict the non B-DNA structure in 3D like cruciforms, hairpin, or G-quadruplex?

xiangjun · « **Reply #1 on:** August 17, 2013, 12:28:34 am »

3DNA/DSSR is an analyzing/modeling toolset. Overall, it does not make 'predictions'. Nevertheless, some of its functionality could prove useful in testing your ideas.

Xiang-Jun

mahesh · « **Reply #2 on:** August 17, 2013, 10:29:42 am »

Can we make a 3D model of Non-B-DNA structure using sequence?

xiangjun · « **Reply #3 on:** August 17, 2013, 10:54:43 am »

The question sounds too general to me. With 3DNA, you can build an arbitrary DNA structure by providing an input file with sequence and desired parameters. See the 2008 3DNA Nature Protocols paper for details.

Xiang-Jun

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Author Topic: Prediction of Non B-DNA structure (Read 88394 times)

mahesh

Prediction of Non B-DNA structure

xiangjun

Re: Prediction of Non B-DNA structure

mahesh

Re: Prediction of Non B-DNA structure

xiangjun

Re: Prediction of Non B-DNA structure