Netiquette · Download · News · Gallery · Homepage · DSSR Manual · G-quadruplexes · DSSR-Jmol · DSSR-PyMOL · DSSR Licensing · Video Overview· RNA Covers

« previous next »
Pages: [1]   Go Down

Author Topic: Prediction of Non B-DNA structure  (Read 14884 times)

Offline mahesh

  • with-posts
  • *
  • Posts: 2
    • View Profile
Prediction of Non B-DNA structure
« on: August 17, 2013, 12:09:29 am »
Hi, is it possible to predict the non B-DNA structure in 3D like cruciforms, hairpin, or G-quadruplex?
Logged

Offline xiangjun

  • Administrator
  • with-posts
  • *****
  • Posts: 1650
    • View Profile
    • 3DNA homepage
Re: Prediction of Non B-DNA structure
« Reply #1 on: August 17, 2013, 12:28:34 am »
3DNA/DSSR is an analyzing/modeling toolset. Overall, it does not make 'predictions'. Nevertheless, some of its functionality could prove useful in testing your ideas.

Xiang-Jun
Logged

Offline mahesh

  • with-posts
  • *
  • Posts: 2
    • View Profile
Re: Prediction of Non B-DNA structure
« Reply #2 on: August 17, 2013, 10:29:42 am »
Can we make a 3D model of Non-B-DNA structure using sequence?
Logged

Offline xiangjun

  • Administrator
  • with-posts
  • *****
  • Posts: 1650
    • View Profile
    • 3DNA homepage
Re: Prediction of Non B-DNA structure
« Reply #3 on: August 17, 2013, 10:54:43 am »
The question sounds too general to me. With 3DNA, you can build an arbitrary DNA structure by providing an input file with sequence and desired parameters. See the 2008 3DNA Nature Protocols paper for details.

Xiang-Jun
Logged
Pages: [1]   Go Up
« previous next »
 

Funded by X3DNA-DSSR, an NIGMS National Resource for Structural Bioinformatics of Nucleic Acids (R24GM153869)

Created and maintained by Dr. Xiang-Jun Lu, Department of Biological Sciences, Columbia University