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Author Topic: Can 3DNA generate PDB files of DNA containing G-T mismatch?  (Read 39623 times)

Offline Doris

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Can 3DNA generate PDB files of DNA containing G-T mismatch?
« on: December 05, 2018, 12:56:31 am »
Hi Xiang,
I try to generate a PDB file using double strand DNA sequence, but the G-T base pair is converted into A-T base pair automatically when I use w3DNA.
May you please guide me that how can I convert the DNA helix contained GT base pair to PDB files?
Thank you ;) .

Offline xiangjun

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Re: Can 3DNA generate PDB files of DNA containing G-T mismatch?
« Reply #1 on: December 05, 2018, 09:27:30 am »
Hi Doris,

Please be specific with your question so others can reproduce it.

What URL did you use for w3DNA? What feature did you try, with what sequence (parameters), and got what result (PDB file)?

Best regards,

Xiang-Jun
« Last Edit: December 05, 2018, 09:29:24 am by xiangjun »

 

Funded by the NIH R24GM153869 grant on X3DNA-DSSR, an NIGMS National Resource for Structural Bioinformatics of Nucleic Acids

Created and maintained by Dr. Xiang-Jun Lu, Department of Biological Sciences, Columbia University