Topics

1

General discussions (Q&As) / Noobie question on building triplex DNA

« on: April 30, 2009, 12:37:51 pm »

Hi everbody!

Sorry for the noobie question, but is it possible to build a triplex DNA from scratch? If not, is it possible to take a .pdb file of a triplex DNA and mutate it to my own sequence? This would involve insertion of an extra residue in the loop region. I would later like to save the new coordinates in .pdb format for molecular dynamics studies.

Thanks in advance for any guidance!

Jason