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Topics - laraibrahim

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General discussions (Q&As) / Intrinsic Curvature of DNA
« on: May 19, 2015, 02:04:21 pm »
Hello,

Thank you for this great program and helpful forum.

Does 3DNA account for the intrinsic sequence dependent curvature of DNA? For example, when I use the reconstruction tool on w3DNA, an A-tract sequence gives a straight segment of DNA. I was expecting something more like this, showing curvature:
http://openi.nlm.nih.gov/imgs/512/281/1176013/1176013_gki699f1.png

Also, is there any way to connect the ends of a linear DNA strand to form a circle?

Thank you in advance,
Lara Ibrahim

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Funded by the NIH R24GM153869 grant on X3DNA-DSSR, an NIGMS National Resource for Structural Bioinformatics of Nucleic Acids

Created and maintained by Dr. Xiang-Jun Lu, Department of Biological Sciences, Columbia University