how to mutate multiple nucleotides with mutate_bases?

[xzhang1999]

Hi,

How can I use mutate_bases to build a homology model using a solved rRNA structure? For example, I want to mutate nucleotides 1-10 in the solved structure with a new sequence "AUAUAUAUAU"?

Thanks much for advice.

Xing

[xiangjun]

Hi Xiang,

Does not the post on mutate_bases help?

Note that you can use the "-e" option to get a list of all nucleotides in your structure, and then modify the output file to suit your needs.

If you still have problems, please be concrete with a specific example.

HTH,

Xiang-Jun