Messages

1

General discussions (Q&As) / Re: change one base pair in a double-strand DNA structure fi

« on: May 26, 2011, 10:18:34 pm »

Dear Dr. Xiang-Jun Lu,

　　Thanks for your help!!

　　Although the two topics in this forum could be well solutions of my problem, I still want to try the component "mutate_bases" for more experiments. Could you share the component with me please? The OS of my working server is Linux and my 3DNA is version 1.5.

　　Thanks for your answer and sharing!

Sincerely,
Chien-Ho,
5/27, 2011

2

General discussions (Q&As) / change one base pair in a double-strand DNA structure file

« on: May 25, 2011, 07:25:53 am »

Dear sir,

　　Thanks for applying the software of 3DNA. Due to my research, here are some questions for using 3DNA:

　　Suppose there is a DNA double-strand structure file in PDB format , is there any possible to change just one base-pair in this structure file by 3DNA?

　　For example, there is a base pair A-T in a DNA structure file. Now I want to replace the A-T base pair by T-A, C-G, or G-C in the A-T position.

　　Due to some other reasons, I don't want to make any difference in the orthogonal coordinates information of other atoms. All I have to do is just replacing one base-pair in this structure file. Could 3DNA handle this case?

　　Thanks for your answering!

Sincerely,
Chien-Ho
5/25, 2011