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MD simulations / How to fix the phosphate on the DNA backbone
« on: November 19, 2016, 02:33:19 pm »
Hi,
I have two DNA structures from PDB. I designed a five-base-pair linker to connect these two DNA structures by using BIOVIA Discovery Studio. I've almost done it but found there are two breaking points on the phosphate backbone. Does anyone know how to fix it? Thanks so much!
Best,
Lester
I have two DNA structures from PDB. I designed a five-base-pair linker to connect these two DNA structures by using BIOVIA Discovery Studio. I've almost done it but found there are two breaking points on the phosphate backbone. Does anyone know how to fix it? Thanks so much!
Best,
Lester