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General discussions (Q&As) / Base Pair Step Parameters

« on: February 16, 2009, 02:41:54 pm »

I´m analyzing an double helix RNA with a modified nucleotide. The effect of the modification pushes one of the bases but doesnt affect complementary one. stragger, proppeler and Buckle are very affected. Since  it affects only one base of the base pair I dont know if  it is correct two analyze roll and tilt. May be its a wrong average of a non-averageble structure.
It would be great If you could tell me if I should take in consideration the base pair step parameters in my analysis.

  Thanks

Regads