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Messages - zhhxu

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Hi Xiang-Jun,

Sorry for the delay in replying. It is convenient to use DSSR to charcterize the structural feature of C2'-endo RNA. Thanks for your suggestion.

Best regards


Zhonghe

2
Hi Xiang-Jun,

Thanks for your prompt reply. I also found some relevant works (JANE S. RICHARDSON) about torsion angle in C2'-endo RNA, including: "RNA backbone is rotameric" , “RNA backbone: Consensus all-angle conformers and modular string nomenclature", and  "Computational methods for RNA structure validation and improvement".  Thanks again for your suggestion.

Best regards,

Zhonghe

3
RNA structures (DSSR) / torsion angle distribution in C2'-endo RNA
« on: June 25, 2020, 10:43:06 am »
Hi everyone:

RNA can adpot two sugar-pucker comformations: C3'-endo and C2'-endo. The latter is lower popolation weight. Have someone noticed any reference about statistical analysis of the torsion angle (i.e alpha-zeta) for C2'-endo RNA. Thank you in advance.

Best regards

zhonghe

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Funded by the NIH R24GM153869 grant on X3DNA-DSSR, an NIGMS National Resource for Structural Bioinformatics of Nucleic Acids

Created and maintained by Dr. Xiang-Jun Lu, Department of Biological Sciences, Columbia University