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Author Topic: Threading DNA  (Read 15672 times)

Offline Dilip

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Threading DNA
« on: June 22, 2009, 01:20:48 pm »
I wonder if it's possible using 3DNA to superpose a given(input) DNA sequence to the conformation of the DNA in the known protein-DNA complexes from the PDB database.
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Offline xiangjun

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Re: Threading DNA
« Reply #1 on: June 22, 2009, 10:17:58 pm »
Quote from: "Dilip"
I wonder if it's possible using 3DNA to superpose a given(input) DNA sequence to the conformation of the DNA in the known protein-DNA complexes from the PDB database.

The short answer is no: 3DNA does not have such functionality built in. However, 3DNA is a tool set that could be used for such purpose. For an example, have a look http://www.ncbi.nlm.nih.gov/pubmed/19289051.

Xiang-Jun
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Funded by the NIH R24GM153869 grant on X3DNA-DSSR, an NIGMS National Resource for Structural Bioinformatics of Nucleic Acids

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