Show Posts

This section allows you to view all posts made by this member. Note that you can only see posts made in areas you currently have access to.


Netiquette · Download · News · Gallery · Homepage · DSSR Manual · G-quadruplexes · DSSR-Jmol · DSSR-PyMOL · DSSR Licensing · Video Overview· RNA Covers

Messages - rkareem

Pages: [1]
1
Bug reports / 5-hydroxy methyl cytosine
« on: September 05, 2018, 06:12:22 am »
Dear Xiang-Jun,

I would like to thank you for making 3DNA and other software's for the analysis of nucleic acid structures.

I used web 3DNA for my structure which has 5- hydroxy methyl cytosine (5HM). When I used web 3 DNA and i got the error message "error in pdb.inp". Later, I used 4pw5 pdb file, which has 5HM (5hc different annotation) and I got the same message.

When I edited my PDB file for 5HM to 5MC (5 methyl cytosine) it worked even keeping the 05 oxygen atom as such.
Therefore, i request you to tweak your web 3DNA software (very user friendly) to accept and process 5HM and other variant of modified cytosine.

I used SNAP to identify DNA-protein interactions and I learned that we don't have reference to cite.

Can I mention like this in my paper citing SNAP.  ( "SNAP from 3DNA suite").

Many thanks
Best regards
Kareem

Pages: [1]

Funded by the NIH R24GM153869 grant on X3DNA-DSSR, an NIGMS National Resource for Structural Bioinformatics of Nucleic Acids

Created and maintained by Dr. Xiang-Jun Lu, Department of Biological Sciences, Columbia University