Messages

1

General discussions (Q&As) / Re: DNA origami

« on: June 20, 2013, 09:56:26 am »

Thanks for a quick reply.

That's interesting. Do you maybe remember the publications regarding model building process? Or have any hints on how to find them?

I have another question as well: can 3DNA be indirectly applicable for such predictions? What I mean is, given there was a good predictor or simulator for DNA origami which would figure out the topology of ssDNA binding to each other at specific places would it be possible to somehow combine it with 3DNA to figure out the exact geometrics of the structure?

Thanks in advance.

2

General discussions (Q&As) / DNA origami

« on: June 19, 2013, 01:10:35 pm »

Hi,

I was wondering if it is possible to use 3DNA to simulate DNA origami structures (as first presented in Rothemund's Nature paper [2006])? What I am particularly interested in is finding out if given the ssDNA sequences (scaffold and staples) could you predict the final origami shape?

Best wishes and kind regards.

Thanks in advance.