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Questions and answers => RNA structures (DSSR) => Topic started by: ktucci on March 09, 2017, 02:32:15 pm

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Title: B Form to A Form Structures
Post by: ktucci on March 09, 2017, 02:32:15 pm

My name is Kaitlin Tucci, from the LCBB Lab at MIT. We currently have B Form structures that we would like to transform into A Form RNA structures utilizing your program. Are there any standing functions on 3D DNA that can help us achieve our goal? Or would it be more advantageous to try to achieve this manually?

Title: Re: B Form to A Form Structures
Post by: xiangjun on March 09, 2017, 02:39:58 pm

Hi,

Thanks for using 3DNA/DSSR and for posting your questions on the Forum.

Quote

We currently have B Form structures that we would like to transform into A Form RNA structures utilizing your program.

It is a bit vague to me as what you want to achieve. Could you be more specific? I remember some molecular dynamics (MD) simulations on B- to A-form transitions.

Xiang-Jun

Funded by the NIH R24GM153869 grant on X3DNA-DSSR, an NIGMS National Resource for Structural Bioinformatics of Nucleic Acids

Created and maintained by Dr. Xiang-Jun Lu, Department of Biological Sciences, Columbia University