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Dear Dr Xu,
I am a Linux Debian user and have recently downloaded the latest x3dna-v2.1. when running the executables, i am getting this message :
"mutate_bases: /lib/libc.so.6: version `GLIBC_2.14' not found (required by mutate_bases)"
Now current debian distribution has 2.11 version, and there is no hope that future debian distributions will go for higher glibc versions.
Is it possible to run x3dna programs with this older version of glibc??
Thanks
Asmita
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Hi Asmita,
Thanks for reporting the problem of running 3DNA v2.1 on Debian. What are your specific Debian settings? What's the output of running "uname -a"? I will look into the issue soon, and your feedback helps in solving the problem.
Xiang-Jun
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Thanks for the response Dr Xu.
output of uname -a :
"Linux hostname 2.6.32-5-amd64 #1 SMP Fri Feb 15 15:39:52 UTC 2013 x86_64 GNU/Linux"
and of lsb_release -a :
Distributor ID: Debian
Description: Debian GNU/Linux 6.0.7 (squeeze)
Release: 6.0.7
Codename: squeeze
Asmita
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Hi Asmita,
Thanks for your feedback. Now I have access to a Debian 6 (x86_64) machine from SBGrid (http://www.sbgrid.org), and did the followings:
~ [501] lsb_release -a
No LSB modules are available.
Distributor ID: Debian
Description: Debian GNU/Linux 6.0.6 (squeeze)
Release: 6.0.6
Codename: squeeze
~ [502] uname -a
Linux sbgrid-dev-vm-17 2.6.32-5-amd64 #1 SMP Sun Sep 23 10:07:46 UTC 2012 x86_64 GNU/Linux
~ [503] ldd --version
ldd (Debian EGLIBC 2.11.3-4) 2.11.3
Copyright (C) 2009 Free Software Foundation, Inc.
This is free software; see the source for copying conditions. There is NO
warranty; not even for MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.
Written by Roland McGrath and Ulrich Drepper.
bin [514] ./mutate_bases
===========================================================================
NAME
mutate_bases -- mutate bases, with backbone conformation unchanged
SYNOPSIS
mutate_bases [OPTIONS] mutinfo pdbfile outfile
DESCRIPTION
perform in silico base mutations of 3-dimensional nucleic acid
structures, with two key and unique features: (1) the sugar-
phosphate backbone conformation is untouched; (2) the base
reference frame (position and orientation) is reserved, i.e.,
the mutated structure shares the same base-pair/step
parameters as the original one.
......
AUTHOR
3DNA v2.1 (c) 2013 Dr. Xiang-Jun Lu (xiangjun@x3dna.org; http://x3dna.org)
===========================================================================
As shown above, the latest 3DNA v2.1 (2013feb22) is working properly on Debian 6.
Recent 3DNA v2.1 Linux 64-bit releases have been compiled on CentOS 5 (x86_64), which has "ldd (GNU libc) 2.5". Moreover, I have just verified that the latest 2013feb22 x86_64 version works on the following settings:
- Scientific Linux 6; ldd (GNU libc) 2.12
- Ubuntu 8.04; ldd (GNU libc) 2.7
- Ubuntu 12.04; ldd (Ubuntu EGLIBC 2.15-0ubuntu10.3) 2.15
Unless I am missing something obvious, you must have been using a previous release of 3DNA v2.1 which was compiled on Ubuntu 12.04. Install the 2013feb22 release of 3DNA v2.1 and report back if that helps.
Does anyone else have such problem with the Linux 64 bit version of 3DNA v2.1 (2013feb22)?
Xiang-Jun
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This version is working perfectly.....and yes, i was using a dec2012 version previously...
Thanks for the help Dr Xu...
Asmita
Funded by the NIH R24GM153869 grant on X3DNA-DSSR, an NIGMS National Resource for Structural Bioinformatics of Nucleic Acids
Created and maintained by Dr. Xiang-Jun Lu, Department of Biological Sciences, Columbia University